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As a key transcription factor, NRF2 regulates antioxidant and detoxifying enzymes, bolstering the cells ability to resist oxidative stress, toxins, and other harmful stimuli, which can improve disease progression and prognosis [154, 155]

Environ Health Perspect 102(4):384389

Pooled estimates often center around roughly 1 to 2 kilograms compared with placebo over several weeks to a few months

Although GPx4-regulated lipid peroxidation was obviously involved in the regulation of ferroptosis in CS-exposed mouse models, no significant difference of NCOA4 and ferritin expression levels was demonstrated based on the alterations of GPx4 status (Supplementary Fig

Wang L, Luo J-Y, Li B, Tian XY, Chen L-J, Huang Y, et al