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Mitochondrial transplantation, mitochondria-derived vesicles (MDVs) and engineered artificial mitovesicles administration are examples of alternative mitochondria-based approaches that aims to preserve cellular bioenergetics and counteract mitochondrial impairment in order to slow or reverse pathological processes, restoring mitochondrial activity mediating the transfer of functional mitochondria or of mitochondrial components [9, 10]

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