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All the SBs evaluation has been recorded using a mirrorless digital camera with a 24.2-megapixel resolution (Sony 7 III, Sony, Japan) coupled with a 40 mm F/2,5 Macro 1:1 fixed focal length lens, and are stored on an external memory device protected by a password, which is known only to the personal involved in the study

Moreover, cellular senescence appears to be increased in SSc patients, and further contributes to CD38 upregulation in lesional tissues 55

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