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BRD4 is a member of the bromodomain and extraterminal (BET) family of chromatin readers that contribute to recruit transcription complexes to acetylated nucleosomes 32

The authors demonstrated that C-terminal sequence modification of the ACTH fragment provides protease resistance while preserving neurotropic properties observed in the rat model, without cortisol release induction

5,6,7 GLP-1 is a peptide produced by the cleavage of proglucagon, mainly synthesized in the intestinal mucosal L-cells, pancreatic islet -cells, and neurons in the nucleus of the solitary tract

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Efficient cargo sorting by ESCRT-I and the subsequent release of ESCRT-I from MVBs requires the subunit Mvb12