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More specifically, the following populations stand the best chances of realizing the benefits of spermidine supplementation: Older people The body's spermidine levels decrease with age, but supplementation can help you maintain optimal levels even as your body's natural reserves diminish.8 People with dietary deficiencies Spermidine is most abundant in foods such as beans, grains, cruciferous vegetables, leafy greens, and fruits.27 The most common spermidine intake value in developed countries is 10-15mg, which falls short of the SNO-recommended 25-30mg per day.2 If your intake values are among the average or lower, a spermidine supplement can help you cover the gap