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Description

The secondary endpoints of the study included pharmacokinetic parameters such as plasma concentration over time, maximum concentration, half-life, plasma clearance, and volume distribution of cagrilintide and semaglutide

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doses were escalated after 5 days from 5 to 10 mg in all multiple-dose trials except in the dosing conditions trial (NCT01572753) [15], in which 10 mg was dosed for 10 days