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Avoid repeated freeze-thaw cycles and protect from light

Proteasome inhibition induces DNA damage and reorganizes nuclear architecture and protein synthesis machinery in sensory ganglion neurons

Nuclear-cytosol extraction kit was purchased from Applygen Technologies Inc (Beijing, China, P1200)

Across these trials, renal serious adverse events or discontinuations due to renal adverse reactions were encountered in less than 1% of participants treated with GENVOYA