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A B12 deficiency is more common in older adults, with past surveys showing that roughly 6% of people 60 years and older arent getting enough vitamin B12

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Research has focused extensively on pigmentation biology via MC1R activation, sexual function pathways mediated through MC4R, and appetite regulation through central melanocortin signalling

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It also shifts melanin synthesis from dark pigment (eumelanin) to a lighter pigment (pheomelanin)