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doi: 10.1016/j.jcmgh.2020.09.013 56 HoG-TAirdRELiuBBoyapatiRKKennedyNADorwardDAet al

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MTHFR (5,10-methylenetetrahydrofolate reductase) Research has shown that some people may be at risk of methylation insufficiency due to reduced MTHFR enzyme function.1 Two common mutations in the MTHFR gene (C677T and A1298C) may contribute to increased levels of homocysteine, a known risk factor for heart disease, atherosclerosis2 and venous thrombosis.3 Those with a genetic mutation in MTHFR will have varying levels of difficulty creating the active form of folic acid which is the important form the body needs to function properly

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