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The main mode of action of CBZ is via the inhibition of sodium channels, although it is contested 9 , since CBZ has also been shown to bind to voltage-gated calcium channels 10 , decreasing the flux of Ca +2 across the neuronal membrane, and also increase the effect of GABA 11,12

The safety and tolerability of HER2-E-CAR-T cells for treating HER2-positive, refractory advanced solid tumors are assessed across three dose groups: low, medium, and high

doi: 10.1021/cr100006x

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