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Nevertheless, gastrointestinal disturbances such as emesis, associated with noradrenergic pathway interference in the brain, and nausea demanded the development of second generations of PDE4 inhibitors to be safe enough for COPD treatment (Boswell-Smith et al., 2006)

Data from at least three biological replicates were analyzed and values are presented as mean standard error of the mean (SEM)

However, we are swayed by commenters that suggested we underestimated the one-time burden of encoding the new data elements in the MRF

Ingredients Aqua (Water), Paraffinum Liquidum (Mineral Oil), Cetearyl Alcohol, Petrolatum, Synthetic Wax, Polysorbate 60, Glycerin, Sorbitan Stearate, Dimethicone, Caprylic/Capric Triglyceride, Glutathione, Ascorbyl Tetraisopalmitate, Diacetyl Boldine, PEG-40 Hydrogenated Castor Oil, Sodium Levulinate, PPG-8-Ceteth-20, PPG-4-Ceteth-20, Butylene Glycol, Glyceryl Stearate, PEG-100 Stearate, Palmitic Acid, Stearic Acid, Levulinic Acid, Carbomer, Xanthan Gum, Disodium EDTA, Tocopherol, Triethanolamine, Citric Acid, Sodium Citrate, Sodium Benzoate, Sodium Metabisulfite, Methylparaben, Parfum (Fragrance), Benzyl Alcohol