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Furthermore, a series of metabolic profile data of gut microbiota in cervical cancer patients summarized that radiation-induced acute intestinal symptoms are characterized by increased fecal concentrations of -ketobutyrate, valine, uracil, tyrosine, trimethylamine N-oxide, phenylalanine, lysine, isoleucine, glutamine, creatinine, creatine, bile acids, aminohippurate, and alanine, accompanied by reduced concentrations of -glucose, n-butyrate, methylamine, and ethanol (77)

These include pro-inflammatory cytokines (e.g., TNF, IL-6) that sustain chronic inflammation ( Figure 1

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[DOI] [Google Scholar] 202.Wang L., Kafshgari M.H., Meunier M

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