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Unfortunately, recent studies have reported global emerging resistance to azole antifungals in clinical and environmental isolates (Rhodes et al., 2022) ( Supplementary File 1 )

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The FDA has given Generally Recognized as Safe (GRAS) status to 9 food colors: However, many of the nine currently approved dyes have raised public health concerns as they are likely carcinogenic, cause hypersensitivity and behavioral problems, or are inadequately tested (Kobylewski & Jacobson, 2010)

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Some patients continue indefinitely under physician supervision with periodic monitoring

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doi: 10.1111/jth.13987 147 ChangCHChungCHHsuCCPengHCHuangTF

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