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Nonmuscle Myosin II Activation Regulates Cell Proliferation, Cell Contraction, and Myofibroblast Differentiation in Keloid-Derived Fibroblasts

Melatonin regulates sleep timing, while DSIP is thought to influence sleep depth and recovery quality

Additionally, the altered ECM affects tissue vascularization and oxygenation, contributing to hypoxia, which further exacerbates the fibrotic process (93)

The rationale involves their complementary mechanisms: BPC-157 provides targeted, local healing support with strong effects on angiogenesis and growth factor signaling