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The mechanistic logic is elegant: in senescent cells, FOXO4 sequesters p53 and prevents it from exerting its apoptotic function

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The effectiveness of home-based therapeutic exercises on adults withfibromyalgia: a systematic review and meta-analysis

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The study then diverged to either a washout day followed by increasing naltrexone doses (1 mg to 25 mg) on days 47 followed by XR-NTX on day 8 or a buprenorphine taper from 6 mg on day 3 to 1 mg on day 7, followed by a 7-day wash-out and XR-NTX on day 15