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BBB permeability alterations are often present before overt clinical symptoms, suggesting that BBB impairment may be a contributing factor to the pathogenesis of various neurological disorders (Figure 3)

Non Surgical Fat Reduction Non-surgical fat reduction treatments have become increasingly popular for those seeking to address stubborn fat without the risks and recovery time associated with traditional methods like liposuction

167 Multiple studies have highlighted the effects of pyruvate metabolism on functional phenotypes across diverse cellular populations (Table 1), such as macrophage polarization, mitochondrial dynamics, and the formation of mitochondria-associated membranes, all of which are indispensable for macrophage function

Integration of AI, particularly through combined learning with multi-omics, spatial omics, histopathological imaging, and other multimodal data, may further improve the accuracy and generalizability of system modeling