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Clinical studies have confirmed that the number of Ki67 + and phosphorylated STAT3 + hepatocytes and cholangiocytes in patients with alcoholic cirrhosis is significantly decreased, indicating that hepatocyte proliferation is inhibited (Horiguchi et al., 2007)

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Chemopreventive effects of the dietary histone deacetylase inhibitor tributyrin alone or in combination with vitamin A during the promotion phase of rat hepatocarcinogenesis

Combined treatment of pancreatic cancer cells with gemcitabine and -MT significantly inhibited proliferation and migration 110

Studies in experimental models suggest that application of grape seed extract to the skin may promote wound healing, but only a very small amount of research has been done on this topic in people, and there isnt enough evidence to conclude whether grape seed extract is helpful for this purpose