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further demonstrated that SLC25A39 and SLC25A40 cooperatively regulate mitochondrial GSH transport, with SLC25A40 expression influenced by Toll-like receptor 4 (TLR4) and receptor for advanced glycation end products (RAGE) signaling pathways 18

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Disclosures: Nalu Navarro-Alvarez: Nothing to Disclose, Osvely Mendez-Guerrero: Nothing to Disclose, Anaisa Carranza Carrasco: Nothing to Disclose, Alma Estanes: Nothing to Disclose, Eduardo Cervantes-Alvarez: Nothing to Disclose, Nathaly Limon-De La Rosa: Nothing to Disclose, Mario Enrique Rendon Macias: Nothing to Disclose, Alfonso Rodriguez Espada: Nothing to Disclose, Aldo Torre: Nothing to Disclose 694 THE INFLUENCE OF GEOGRAPHICAL DIFFERENCES AND COVID-19 ON HEPATIC-FAILURE RELATED MORTALITY RATES Qasim Chohdry 1 Saad Khan 1 Sophia Hussain 1 Muhammad Chohdry 2 Islam Mohamed 1 Kiel Corkran 1 1 University of Missouri- Kansas City School of Medicine, 2 University of Kansas School of Medicine Background: Several studies have looked at the relationship between geographic location and prevalence of diseases

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For example, in a sample of patients with established schizophrenia, Iwata et al