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NasirOWangKFollerMBhandaruMSandulacheDArtuncFet al

The GCH1/BH 4 /DHFR system suppresses ferroptosis The metabolic change that occurs in cancer cells often requires endogenous antioxidants to reduce toxic lipid oxidation

Figure 2 6 Pathologic relationship between ferroptosis and neurodegenerative diseases The hallmark of neurodegenerative diseases is the gradual death of neurons and are brought on by an accumulation of oligomers and aggregates of misfolded proteins (Menzies et al., 2020)