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164 The proportion of responders rose from 33.3% at week 1 to 90% one month after completion of 12 instillations and then diminished to 16.7% by 6 months after the last instillation

An imbalance in the intestinal barrier structure can flare up into an uncontrollable immune reaction in the intestinal microenvironment or allow the unrestrained growth of microbiota, which leads to various diseases, including intestinal inflammatory disorders, extra-intestinal autoimmune diseases such as rheumatoid arthritis and multiple sclerosis, and metabolic disorders such as diabetes and obesity 4,5,6

It is commonly discussed in wellness and performance spaces for its potential role in recovery and soft tissue support

95% CI 1.791.86)

Drmic, D., Kolenc, D., Ilic, S., Bauk, L., Sever, M., Vukojevic, J.,