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Description

Dysregulated innate immunity with strong activation of T helper (Th)1 and Th17 pathways, increased tumour necrosis factor-, interleukin (IL)-1 , IL-17 and IL-23 pathways, together with an altered microbiome, contribute to chronic inflammation and abscess formation

This case series investigates the synergistic use of guanfacine, N-acetylcysteine (NAC), and donepezil (GND) administered alongside ongoing cognitive rehabilitation, with treatment effects evaluated through pre- and post-intervention Montreal Cognitive Assessment (MoCA) scores