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Kynurenic acid, an endogenous allosteric inhibitor of NMDAR 63

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Possible anti-aging effect on skin cells

Studies on Wister rats also highlight caffeines neuroprotective role, where it improved memory performance in spatial learning tasks, counteracted STZ-induced cognitive deficits, and reduced neuroinflammation and oxidative stress [94, 114, 166, 307]

For instance, a study published in the journal Hepatology indicated that ibuprofen administration in mice led to decreased hepatic glutathione levels, suggesting that NSAIDs could contribute to glutathione depletion under certain conditions