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doi: 10.1126/science.aar7734 495 RochmanC

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demonstrated through in vivo experiments in mice that the number of osteoclasts decreased, bone resorption decreased, bone mass increased, biomechanical strength was improved, and the occurrence of cancellous femoral bone was reduced in mice that were knocked out or inhibited (106)

These results indicate that AIMP3 works as an important signaling molecule in tumorigenesis (Fig

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