what is glutathione used for in ecoli Systematic manipulation of metabolism Escherichia coli improved glutathione production | Microbial Cell Factories The Glutathione System: A Journey

In the case of the colitis-associated cancer (CAC) mouse model, IKK genetic deletion in intestinal epithelial cells greatly reduces the incidence of tumors through the increase of apoptosis [52], while its KO in the macrophage significantly reduces tumor size by suppressing the expression of pro-inflammatory factors [53, 54]

Alveolar macrophages in neonatal mice are inherently unresponsive to Pneumocystis murina infection

doi: 10.1016/j.molmed.2022.02.003 250 YangKZengLZengJDengYWangSXuHet al

The neurociliin-1 (NRP-1) receptors are largely found in tumor and vascular tissues

Also, when cells acquire their cysteine via GSH breakdown, they are no longer sensitive to inhibitors of cystine uptake