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Acetaminophen at low doses depletes airway glutathione and alters respiratory reflex responses Smith 2013 The FASEB Journal Wiley Online Library Mechanism of acetaminophen induced hepatotoxicity. High dose of Download Scientific Diagram PharmGKB summary: Pathways of acetaminophen metabolism at the therapeutic versus toxic doses PMC GSH reduces NAPQI, the metabolite responsible for hepatotoxicity in acetaminophen toxicity. Toxic doses increase oxidation into NAPQI, overwhelming glutathione. How does ethanol interfere with acetaminophen metabolism? Image: https: t.co 6EY9dIwLXY Metabolic fate of acetaminophen. The vast majority of acetaminophen Download Scientific Diagram
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