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Compared to an isocaloric control diet, the high carbohydrate-high calorie diet was safe, tolerable and effective in delaying weight loss and prolonging survival in the patients (Wills et al., 2014)

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A series of combinations of deaminase, reverse transcriptase (RT), or a transcriptional repressor/activator with Cas9 subsequently achieved unprecedented benefits, such as the expression/activation of specific or multiple genes, DNA base pair conversions, or transversions

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