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Researchers have demonstrated that amino acid metabolism is related to ferroptosis and that CCH can cause neuronal depolarization to release excess glutamate during the pathogenesis of VD, resulting in excitotoxicity, and high levels of glutamate inhibit the function of System Xc-

Methods: In this study, Mendelian randomization (MR) analysis, primarily inverse-variance weighted MR, was used to assess the causal effect of six endogenous and five exogenous diet-derived antioxidants on the risk of six cancers

NRF-1 is essential for enhancing the transcription of proteins and enzymes involved in various mitochondrial activities, including mitochondrial biogenesis, maintenance of mitochondrial DNA, oxidative phosphorylation, and the regulation of respiratory chain complexes (Choi et al

& Sutton, G

Banerjee et al., 2021)