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Limiting the GSH formation by inhibiting system x c - is a promising approach to kill tumor cells due to the excessive active metabolism and sustained oxidative stress [43]

Specifically, GABA decreased in OTC for the signal-from-noise task, indicating that disinhibition could facilitate the extraction of feature from noise, potentially through an amplification of neuronal gain

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Lipid biosynthesis predominantly occurs in the liver and adipose tissue, utilizing acetyl-CoA as the central substrate

In an assay mixture 100 g protein was incubated in a 1 ml solution containing 5 mM manganese chloride or MnCl 2 , 0.1 mm DTT, 0.1 mM p-coumaric acid, 0.05 mM NADP(H), 30 mM sodium acetate buffer (pH 7.5) and incubated under dark