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The drugs are believed to be located preferentially in the palisade layer, and the increase in temperature causes dehydration of the PEO groups, bringing them closer and consequently reducing the space available for the drugs in this region of the micelle

J Genet Eng Biotechnol

Unlike gastric bypass, the sleeve does not reroute the small intestine, so malabsorption is generally less severe however, nutritional deficiencies remain a meaningful risk and are a well-established cause of peripheral neuropathy, including symptoms such as thigh numbness

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