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Approximately 1.1 billion compounds were screened via this platform, and multiple candidate compounds with geroprotective properties that demonstrate structural novelty and target specificity were successfully identified

If normally distributed, the t -test was applied to compare means

132 Finally, a study examining the impact of AUD on patients with asthma and COPD found that those with AUD were more likely to present with respiratory failure, require mechanical ventilation, have longer hospital stays, and have higher health care costs than those without AUD, which suggests that treating AUD in this patient population may improve disease outcomes and reduce health care utilization

doi: 10.1016/j.bbrc.2004.06.123 52 TilgHVannierEVachinoGDinarelloCAMierJW

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