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With the exception of TLR3, all TLRs predominantly signal through the MyD88-dependent pathway

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In addition, tumor-on-a-chip integrates tumor and stromal cells instead of healthy tissue cells, to mimic invasive tumor behaviour and TME dynamics (Li et al., 2023a

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perfoliata also dose-dependently inhibited the phosphorylation of extracellular regulatory kinase (ERK) and c-Jun N-terminal kinase (JNK) in cells ( The P815 cell line is a mast cell model