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The rate of protein synthesis in hematopoietic stem cells is limited partly by 4E-BPs

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One example of this comes from a study performed in the Amazon fish tambaqui ( Colossoma macropomum ), in which low water pH (pH 4.0) significantly reduced the abundance of gut Flavobacterium while the ratio of Firmicutes and Bacteroides were significantly increased (Sylvain et al., 2016)