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[33] In chronic inflammatory bowel diseases, including Crohns disease, systematic reviews (including Cochrane reviews) have concluded that current randomized evidence is insufficient to support glutamine supplementation for inducing remission or modifying disease progression, and further well-powered clinical trials are required

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Studies are not entirely consistent, but they mostly report an increase in Akkermansiaceae and Methanobacteriaceae, and a decrease in SCFA-producing Bacteroidetes and Clostridia clusters (Atarashi et al., 2011

Exposure to pollutants can rarely be totally avoided and, as most of them (ozone, particulate matters, and nitrogen and sulfur oxides, etc.) are pro-oxidants and thus pro-inflammatory, their influence on asthma exacerbations can be partially limited by an administration of anti-oxidant vitamins, which has been described above

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