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Precautions: Stop using if you experience rash, redness, or itching, and see a doctor if these symptoms don't go away

Material and methods Cell culture Human hepatocellular carcinoma (HepG2) (ATCC, HB-8065) were maintained in DMEM (4.5 g/l glucose, pyruvate) (Gibco), supplemented with 10% fetal bovine serum (PAA Laboratories) and penicillin/streptomycin (25 g/ml each, Gibco) at 37 C, 5% CO 2

Immunoprecipitation was performed with SF3B1 antibody (MBL, MB-221-3, 5 l)

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Notably, CagriSema is the only one of the three that brings in the amylin system the others stay within the incretin/glucagon family