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Baum P, Kosacka J, Estrela-Lopis I, Woidt K, Serke H, Paeschke S, et al

Lamichhane, S

A second cohort were injected with B-017 (1.6 mg kg 1 BW in 50 l NaCl) or the negative control peptide intraperitoneally (1.6 mg kg 1 BW in 50 l NaCl) on day 1, day 3, day 5, and day 7 post infarction

PON1 is susceptible to being partially inactivated by the metabolic products of oxidative stressspecifically, by oxidized glutathione (GSSG) through the process of S-glutathionylation and by products of lipid peroxidation, which can also react with the free sulfhydryl group of the enzyme (Aviram et al., 1999