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In addition, these dots decrease the levels of inflammatory cytokines and suppress protein expression 66

Annu Rev Pharmacol Toxicol (2020) 60:63759

Insights on the NRG Trial

Lipidomic and transcriptomic analyses revealed that lipophagy was activated by Atg5 in HCECs exposed to HS, driving ferroptosis in CECs and thus inducing corneal damage and ocular surface inflammation (123)