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T.MorrowE.LuoN.et al (2013)

10.3389/fncel.2014.00384 137 StephensonE.NathooN.MahjoubY.DunnJ

Using a cold compress with ice cubes will constrict the dilated blood vessels causing dark circles, reducing their appearance

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Rather than being associated with MDD status, some data suggest that shortened telomeres may actually reflect duration of exposure to depressive symptoms 24 , the severity of depressive symptoms 10 , or stress-related physiological or metabolic dysregulation including metabolic syndrome, inflammation and/or oxidative stress 7,12,24,31,32,33,34