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FBXO22 helps mark certain proteins for breakdown inside cells

Disclosures: Naoya Tsumura: Nothing to Disclose, Kazuo Imagawa: Nothing to Disclose, Ken Kato: Nothing to Disclose, Osamu Ohara: Nothing to Disclose, Ryuta Nishikomori: Nothing to Disclose, Tatsuki Mizuochi: Nothing to Disclose 2484 DEEP PHENOTYPING OF A NORTH AMERICAN COHORT OF BILE ACID SYNTHETIC DISORDERS Alyssa Kriegermeier 1 Krupa Mysore 2 Estella Alonso 1 Aki Asai 3 Kevin Bove 3 Laura Bull 4 Nathan Goodrich 5 Steve Guthery 6 Sanjiv Harpavat 7 Simon Horslen 8 Evelyn Hsu 9 Karen Jones 10 Binita Kamath 11 Saul Karpen 12 John Magee 13 Jean Molleston 14 Alexander Miethke 15 Philip Rosenthal 4 Ronald Sokol 16 Kenneth Setchell 3 Benjamin Shneider 17 Richard Thompson 18 Pamela Valentino 19 Wen Ye 10 Kathleen Loomes 20 Rohit Kohli 21 , 1 Ann and Robert H

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Laser treatments, including the 1064 nm emitting neodymium:YAG, CO 2 , Q-switched ruby, and Erbium:YAG lasers, are effective for treating POH from pigmentary and vascular causes

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