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Histone acetylation, which is well characterized, is controlled by the opposing activities of histone acetyltransferases (HATs) and histone deacetylases (HDACs)

Different classes of flavonoids possess distinct structural features, resulting in variations in their metabolic pathways and bioavailability within the body ( 3 The regulatory effect of flavonoids on immune cells 3.1 Macrophages Macrophages are a type of innate immune cells with phagocytic and antigen-presenting functions, playing a crucial role in various diseases (83)

Consequently, enhancing the sensitivity of chemotherapy by inhibiting the uptake of LAT2-mediated amino acids to reduce CD47 and by enhancing the infiltration and phagocytosis of tumour cells by macrophages has emerged as a potential strategy for the treatment of cancer

PMID 28018972

Remember that bile is your bodys natural laxative