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Sex as a biological variable: we utilized only male rats to maximize the satellite cell yield per gram of muscle tissue and individual animal (Figure 1d,f and supplementary Figure 1a) and male mice to examine the preventive effect of oral administration of glutathione trisulfide (GSSSG) and lipoic acid trisulfide (LASSS) (Figure 2e) on disuse-induced nitration-dysfunction of ECM-bound HGF

The lack of FDA approval for human use and the need for higher doses in some experimental settings underscore the importance of evaluating safety and efficacy under strict medical supervision

These findings suggest that suppression of the JAK2/STAT3 axis is a key mechanism by which EC attenuates inflammatory responses in macrophages (Yang et al., 2015)

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