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Kennedy and other advocates say that, anecdotally, individual patients have benefited greatly from these experimental substances, and if people are going to use them, then its safest to get them from a licensed pharmacy that sources its ingredients from FDA-registered manufacturers and wholesalers

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[DOI] [PMC free article] [PubMed] [Google Scholar] 287.Ekwomadu T., Mwanza M., Musekiwa A

From a mechanistic perspective, herbal antidepressants frequently modulate monoaminergic systems by either inhibiting MAO-A/B or augmenting the availability of serotonin, norepinephrine, and dopamine