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doi: 10.1016/j.cca.2013.11.037 122 TanYMGaoYTeoGKohHTaiEKhooCet al

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CCBs cause natriuresis by raising glomerular filtration pressure, dilating afferent arterioles, and increasing renal blood flow in the kidney ( Beta-blockers (BBs) are among the drugs that prevent the effects of endogenous catecholamine on -adrenergic receptors

However, in the complex molecular processes that characterize tumorigenesis, iron also plays a central role in ferroptosis, a form of non-apoptotic regulated cell death characterized by the lethal accumulation of lipid peroxidation products and ROS derived from iron metabolism (362, 363)