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Finally, NAD glycohydrolases (or NADases) generate cyclic ADP ribose (cADPr) from NAD + , also releasing NAM in the reaction [3,6]

FASEB J 23(2):351361 Guglin ME, Koul D (2006) Cardiovascular effects of erythropoietin: anemia and beyond

Lin S, Del Razo LM, Styblo M, Wang C, Cullen WR, Thomas DJ (2001) Arsenicals inhibit thioredoxin reductase in cultured rat hepatocytes

This suppression of hACE2 and TMPRSS2 expression suggests a potential mechanism by which hesperidin inhibits viral entry into these lung cells

NADPH is known to be tightly bound to mammalian catalase, and prevents inactivation of catalase by H2O2 (Fig