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Preclinical studies have shown promising results: Specific strains such as Bifidobacterium breve and Lactobacillus plantarum reduce microglial activation, increase anti-inflammatory cytokines like IL-10, promote neurogenesis, and enhance cognitive performance in rodent models of AD [624, 625]

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The balance between activation and detoxification by xenobiotic-metabolizing enzymes is often a key determinant of chemical toxicity, and often the basis for organ or species differences in toxicity

A study [199] demonstrated that the presence of intra-myocardial hemorrhage (IMH) in patients with ST-segment elevation myocardial infarction who underwent interventional therapy reperfusion for the first time was related to residual myocardial iron at follow-up, suggesting a link between iron metabolism and reperfusion injury

Techniques involving the growth of chlorella on filtered water would likely avoid this contamination and could provide a good option for treatment