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CoQ10 augments rosuvastatin neuroprotective effect in a model of global ischemia via inhibition of NF-kappaB/JNK3/Bax and activation of Akt/FOXO3A/Bim cues

Sublingual/Orobuccal: Direct absorption through mucous membranes

10.1021/tx9902082 16

The in vivo results corroborated the in vitro data, showing that EW modulated apoptosis-related proteins by reducing Bax levels and increasing Bcl-2 expression (Fig