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It upregulates miR-203a3p, decreases GRP78, and modulates the Endoplasmic Reticulum Stress pathway

Abstract Purpose This study had two primary aims: (1) to evaluate the clinical efficacy of fluoroscopically-guided subchondral autologous bone marrow aspirate concentrate (BMAC) injection for reducing pain and improving function in patients with knee osteoarthritis (OA)-associated bone marrow lesions (BMLs), we hypothesized significant improvements across validated outcome measures at 12 months

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A vitamin as neuromodulator: Ascorbate release into the extracellular fluid of the brain regulates dopaminergic and glutamatergic transmission

10.1016/j.enmm.2023.100872 106 KhanI