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34 Exosomes are involved with angiogenesis, immune responses, cell adhesion and migration, inflammatory response, metabolic adaptation, fetal development, and intercellular communication

it can be calculated by homeostasis model assessment of IR (HOMA-IR) as (fasting insulin mU/l) (fasting glucose mmol/l)/22.5 (20)

Replacement therapy for hypothyroidism with thyroxine alone does not ensure euthyroidism in all tissues, as studied in thyroidectomized rats

78 A caveat of the use of pancaspase inhibitors is the fact that they generally require the solvent dimethyl sulfoxide (DMSO), a potent inhibitor of P450 enzymes, 79 and higher doses of caspase inhibitors may inhibit other proteases through off-target effects

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