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Selective metabolic activity: Research has documented that the C-terminal GH fragment exhibits activity in lipid metabolism pathways in laboratory models, particularly in relation to adipocyte biology and lipolytic enzyme activity, without the full growth-promoting and insulin-antagonistic effects of the complete GH molecule

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These include sufficient production of the neoantigen, strong binding affinity to the patients HLA molecules, and effective recognition by the patients T cells (Harndahl et al., 2012)