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Although therapeutic strategies targeting the immune-inflammatory response (e.g., corticosteroids and immunosuppressive drugs) are effective in non-PF interstitial lung disease, they have no discernible impact on the fibrotic process in PF [31]

control, 194) showed no significant effect of NAC supplementation on SHGB levels (WMD: 168 nmol/l, 95 % CI (210, 545), P = 0383) (online Supplementary Fig

Another study reported the interplay between ROS and SIRT1 in cell death during EV71 infection, and inhibition of ROS by NAC was shown to reduce EV71 propagation 149

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doi: 10.1016/S0014-5793(02)02702-3