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To date, niacinamide, ascorbic acid, resveratrol, azelaic acid, and kojic acid are considered alternative topical agents that have been reported to exhibit depigmenting properties without severe adverse effects

A reduction in Faecalibacterium prausnitzii , an anti-inflammatory species has been reported in subjects with cirrhosis (92, 93)

In addition to its crucial role during development, D3 activity is also important in regulating thyroid hormone action at the cellular level in different pathophysiological conditions

An inverse correlation has been observed between melatonin and the risk of development of breast cancer

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